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Spectrum of ultraviolet radiation on human B and T lymphocyte viability
Author(s) -
CRIPPS D.J.,
HOROWITZ S.,
HONG R.
Publication year - 1978
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1978.tb01458.x
Subject(s) - reprint , library science , medicine , family medicine , computer science , physics , astronomy
Summary Human lymphocytes were irradiated with ultraviolet radiation (UV) of various wavelengths. Selective T cell killing was achieved with a dose of 0·1‐0·067 J/cm 2 with UVC (a germicidal lamp) or 254 nm monochromatic radiation while preserving B cell function. Irradiation of lymphocytes with UVA up to 9 J/cm 2 caused no apparent T and B cell killing. Irradiation with monochromatic 280 and 296 nm radiation (UVB) showed similar susceptibility of both T and B cells with killing occurring with less than 0·5 J/cm 2 .