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Malacoplakia of the skin
Author(s) -
ARUL K.J.,
EMMERSON R.W.
Publication year - 1977
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1977.tb01556.x
Subject(s) - malacoplakia , histiocyte , pathology , rheumatoid arthritis , medicine , connective tissue , lesion , stroma , immunology , immunohistochemistry
Summary A case of malacoplakia of the vulval skin is reported in a patient receiving systemic steroids and immuno‐suppressive drugs for severe rheumatoid arthritis. The microscopic abnormality of this lesion consisted of a granulomatous infiltrate composed of histiocytic cells rich in PAS positive granules with inclusions known as Michaelis‐Guttmann bodies. The cells were embedded in a scanty connective tissue stroma infiltrated by lymphocytes and plasma cells.