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Measurement of 59 Fe absorption and retention in patients with familial chronic muco‐cutaneous candidiasis using the method of whole body counting
Author(s) -
HIGGS JANET M.,
SMITH PAUL,
SMITH TERRY
Publication year - 1976
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1976.tb01444.x
Subject(s) - medicine , iron deficiency , etiology , absorption (acoustics) , gastroenterology , physiology , excretion , dermatology , anemia , materials science , composite material
Summary A study of 59 Fe absorption was carried out on fourteen patients with familial chronic muco‐cutaneous candidiasis (FCMC) using the method of whole body counting. 59 Fe retention was also determined in eleven of these individuals, for periods up to 133 days. Eight of fourteen patients absorbed less than 6% of the 59 Fe administered. Six of these subjects had previously shown evidence of impaired iron tolerance in the presence of latent iron deficiency. Iron excretion was not increased in any of the individuals studied. These observations support the view that iron absorption may be impaired in some patients with FCMC and could be a contributory factor in the aetiology of the latent iron deficiency associated with the condition.