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Disease severity impairs sleep quality in allergic rhinitis (The SOMNIAAR study)
Author(s) -
Colás C.,
Galera H.,
Añibarro B.,
Soler R.,
Navarro A.,
Jáuregui I.,
Peláez A.
Publication year - 2012
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.2011.03935.x
Subject(s) - medicine , somnolence , asthma , quality of life (healthcare) , logistic regression , prospective cohort study , clinical significance , sleep disorder , restless legs syndrome , physical therapy , insomnia , adverse effect , psychiatry , nursing
Summary Background Sleep is impaired in allergic rhinitis ( AR ) patients, with subsequent effects on daytime performance and health‐related quality of life ( QOL ). Sleep quality in AR has rarely been considered through validated tools and consensus classifications. Objective To evaluate sleep quality and daytime somnolence in AR patients, and to estimate its relationship to disease severity according to Allergic Rhinitis and Its Impact on Asthma ( ARIA ) conventional and modified classifications, as well as in terms of QOL and comorbidities. Methods Allergic rhinitis adult patients were evaluated through a prospective, observational, multicentre survey in S pain. Symptoms were assessed using the Total Symptoms Score ( TSS ), specific QOL by the Rhinitis Quality of Life Questionnaire ( RQLQ ), sleep quality by P ittsburgh scale, and diurnal somnolence by a scale based on E pworth's, all recorded in a unique visit. Results A total of 2275 patients were included. According to ARIA criteria, 50.2% had persistent and 49.8% intermittent rhinitis, whereas 87.6% were classified as moderate‐severe and 12.4% as mild; 52.8% had poor sleep quality, with a global median score for P ittsburgh scale of 6 (normal < 5) and 21.1% suffered from excessive diurnal somnolence. Correlation between P ittsburgh scale and RQLQ was moderate ( r = 0.54). Among symptoms, nasal obstruction and concomitant asthma mainly, contributed to bad sleep quality. In a logistic regression model, moderate‐severe rhinitis and nasal obstruction were all associated with a worse sleep quality. Conclusions and clinical relevance Sleep quality is altered in AR patients. Sleep quality was worse in moderate‐severe, and particularly in severe AR . Nasal obstruction and RQLQ deterioration are associated with a poorer sleep quality. Sleep impairment is common in allergic rhinitis, particularly in more severe forms. Nasal obstruction and concomitant asthma should be considered as contributing factors. Capsule summary This is a large epidemiological survey of patients with allergic rhinitis showing a strong relationship between disease severity, as assessed by a consensus classification, and sleep impairment, as measured by a validated sleep quality tool.