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Association of childhood perennial allergic rhinitis with subclinical airflow limitation
Author(s) -
Ciprandi G.,
Capasso M.
Publication year - 2010
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.2009.03399.x
Subject(s) - medicine , spirometry , subclinical infection , allergy , asthma , vital capacity , sensitization , house dust mite , rhinomanometry , bronchoconstriction , risk factor , lung volumes , atopy , nose , gastroenterology , dermatology , immunology , allergen , lung , lung function , surgery , diffusing capacity
Summary Background Allergic rhinitis (AR) is a relevant risk factor for the onset of asthma, and a close association exists between the nose and the bronchi. Recently, it has been evidenced that the duration of AR and mite allergy represent high risks for spirometric impairment in allergic adults. Aim To evaluate a group of AR children, without bronchial symptoms, to investigate spirometric impairments. Methods Two hundred children with moderate‐severe AR were consecutively evaluated. Clinical examination, skin prick test, and spirometry were performed in all children. Results Thirty‐one percent of the children had forced expiratory flow at 25% and 75% of the pulmonary volume (FEF 25–75% )<80% of the predicted values and 11% had both forced expiratory volume in 1 s and FEF 25–75% <80% of the predicted values. Rhinitis duration and sensitization to house dust mites were significantly associated with impaired values of these spirometric parameters. Conclusion This study highlights the close link between the upper and the lower airways and the role of some risk factors, such as long duration and mite sensitization, as early prognostic markers of bronchial involvement in children with ARand perceiving nasal symptoms alone. Cite this as : G. Ciprandi and M. Capasso, Clinical & Experimental Allergy , 2010 (40) 398–402.