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Ethanol metabolite acetic acid as causative agent for type‐I hypersensitivity‐like reactions to alcohohc beverages
Author(s) -
BOEHNCKE W.H.,
GALL H.
Publication year - 1996
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1996.tb00648.x
Subject(s) - acetic acid , context (archaeology) , metabolite , allergen , ethanol , chemistry , allergy , alcohol , food science , medicine , pharmacology , immunology , biochemistry , biology , paleontology
Summary Background Adverse reactions to alcoholic beverages are common and more frequently mediated by immunological mechanisms than previously thought. Objective To elucidate relevant allergens in this context we studied patients with an informative medical history. Methods This report describes a comprehensive allergological approach in a patient exhibiting type‐I hypersensitivity‐like reactions towards beverages and medication containing alcohol, and salad dressings with acetic acid. Results The ethanol metabolite acetic acid was found to yield positive prick test results in concentrations not eliciting reactions in healthy and atopic controls. Conclusion Among other ethanol metabolites, acetic acid is a potential allergen in the context of hypersensitivity towards alcoholic beverages.