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Effect of nasal anaesthesia on lacrimal function after nasal allergen challenge
Author(s) -
LÖTH S.,
BENDE M.
Publication year - 1994
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1994.tb00249.x
Subject(s) - medicine , lidocaine , allergen , nose , anesthesia , reflex , nasal administration , tears , corneal reflex , nasal cavity , allergy , dermatology , surgery , immunology
Summary Ocular symptoms in allergic rhinoconjunctivitis arise partly from direct contact of the allergen with the conjunctiva and presumably partly from a naso‐lacrimal reflex. The aim was to study the importance of this reflex in allergic rhinitis after topical anaesthesia of the nose. Ten patients with allergic rhinoconjunctivitis lo birch pollen were challenged with increasing intranasal doses of allergen until allergic symptoms occurred. The same dose of allergen was used in two other provocations, when the nasal cavity was anaesthetized with topical lidocaine in a double‐blind rundomized cross‐over manner. The effect on the eyes was evaluated by Shirmer's test, a routine method for measuring tear production. Lidocaine per se and/or allergen challenge had no significant effect on tear production. The naso‐lacrimal reflex was not involved in the eye symptoms, in allergic conjunctivitis.