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The importance of appropriate challenges in diagnosing food sensitivity
Author(s) -
KAPLAN M. S.
Publication year - 1994
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1994.tb00234.x
Subject(s) - medicine , food allergy , immunoglobulin e , placebo , oral food challenge , allergy , food hypersensitivity , intensive care medicine , immunology , antibody , alternative medicine , pathology
Summary Two patients with clinically significant immunoglobulin E (IgE) mediated reactions to cow's milk which occur only under special circumstances are described. Although double‐blind, placebo‐controlled food challenges or open food challenges are generally very helpful, certain patients who react only under special circumstances might be missed when these office tests are used. The two reported incidences occurred in older children who seemed to outgrow their cow‐milk allergy but still had clinically significant allergic reactions under certain circumstances.