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Immediate and delayed allergy to nickel with contact urticaria, rhinitis, asthma and contact dermatitis
Author(s) -
ESTLANDER T.,
KANERVA L.,
TUPASELA O.,
KESKINEN H.,
JOLANKI R.
Publication year - 1993
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1993.tb00327.x
Subject(s) - nickel allergy , provocation test , medicine , contact dermatitis , dermatology , allergy , contact urticaria , contact allergy , asthma , patch test , immunoglobulin e , allergic contact dermatitis , radioallergosorbent test , atopic dermatitis , immunology , allergen , pathology , antibody , alternative medicine
Summary A 27‐year‐old woman had for 2 years performed manual grinding of metal castings that contained nickel. She had previously had allergic contact dermatitis from nickel but started to get contact urticaria, rhinitis and asthmatic attacks at work. The symptoms disappeared at weekends and on holiday. Scratch chamber tests, open tests, specific IgE determinations (RAST), and RAST‐inhibition test indicated that she had developed an IgE‐mediated allergy to nickel; the bronchial provocation reaction with NiSO 4 was, however, a late one. Patch tests confirmed her allergic contact dermatitis to be caused by nickel. This is the first patient, to the best of our knowledge, reported to have developed allergic contact dermatitis, allergic contact urticaria, rhinitis and asthma from nickel.