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How allergenic are hypoallergenic infant formulae?
Author(s) -
RUGO E.,
WAHL R.,
WAHN U.
Publication year - 1992
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1992.tb00180.x
Subject(s) - hypoallergenic , provocation test , casein , hydrolysate , medicine , allergen , food science , allergy , infant formula , immunoglobulin e , immunology , antibody , chemistry , biochemistry , pathology , alternative medicine , hydrolysis
Summary In a comparative study six different protein hydrolysates, marketed as ‘hypoallergenic’ infant formulae were investigated by skin prick tests, RAST, RAST inhibition and titrated provocation tests. Whey hydrolysates containing a high percentage of larger peptides were found to have the highest capacity to induce positive skin tests, provocation tests and. To bind to human serum IgE antibodies of cow's milk allergic children. Casein hydrolysates appeared to have the least residual allergenic activity. We recommend that ‘hypoallergenic’ formulae should be tested in each case, before being prescribed to cow's milk sensitive children.