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Allergic reactions to the Australian paralysis tick, Ixodes holocyclus : diagnostic evaluation by skin test and radioimmunoassay
Author(s) -
GAUCI M.,
LOH R. K. S.,
STONE B. F.,
THONG Y. H.
Publication year - 1989
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1989.tb02384.x
Subject(s) - tick , medicine , radioimmunoassay , immunoglobulin e , immunology , ixodes , allergy , skin test , dermatology , virology , pathology , antibody , tuberculosis
Summary Allergic reactions to Ixodes holocyclus are well recognized but poorly defined. Tick‐bite reactions in 42 individuals in this study fell into six classes. Skin‐prick tests and radioimmunoassay (RIA) indicated that all systemic hypersensitivity (class 3) and atypical reactions (class 4) were IgE‐mediated. Some 73% of the large local reactions (class 2) and only 12.5% of the small local reactions (class 1) were associated with IgE specific for tick allergens. Subjects who reported heavy exposure to tick‐bite were more likely to have positive RIA values ( P <0.05). There was an association between the individual's atopic status and tick allergy ( P >0.05).