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Prevalence of atopy is unrelated to presence of inflammatory bowel disease
Author(s) -
TRONCONE R.,
MERRETT T. G.,
FERGUSON ANNE
Publication year - 1988
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1988.tb02850.x
Subject(s) - atopy , medicine , ulcerative colitis , inflammatory bowel disease , immunology , proctitis , immunoglobulin e , pathogenesis , disease , allergy , gastroenterology , antibody
Summary The prevalence of atopy (assessed by prick testing and serum IgE measurement), and of symptoms associated with atopy, has been defined in 122 patients with inflammatory bowel disease (IBD) and 103 age‐matched controls. History analysis for atopic symptoms, and serum IgE levels, showed no differences between controls and IBD patients, or IBD subgroups (Crohn's disease, ulcerative colitis, ulcerative proctitis). Both in controls and in IBD patients, the prevalence of positive skin tests was higher in young people (aged > 30) than in others; taking account of age distribution within the groups, there were no differences between controls and IBD patients, or subgroups, in the prevalence of positive skin tests. Our findings do not support the hypothesis that reaginic hypersensitivity plays a significant role in the pathogenesis of IBD.