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Isolated late asthmatic reaction due to nickel sulphate without antibodies to nickel
Author(s) -
MALO J. L.,
CARTIER A.,
GAG G.,
EVANS S.,
DOLOVICH J.
Publication year - 1985
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1985.tb02261.x
Subject(s) - nickel , occupational asthma , reactivity (psychology) , asthma , inhalation , antibody , medicine , immunology , chemistry , toxicology , anesthesia , biology , pathology , organic chemistry , alternative medicine
Summary A worker with occupational exposure to nickel developed asthma a few months after starting work. Skin prick tests to nickel sulphate were negative. Inhalation challenge with nickel sulphate, at a concentration of 10 mg/ml for 30 min induced a late asthmatic reaction, starting 3 hr after the end of exposure leading to severe nocturnal attack. Tests for antibodies with nickel reactivity were negative.