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Baker's asthma
Author(s) -
BLOCK G.,
TSE K. S.,
KIJEK K.,
CHAN H.,
CHANYEUNG M.
Publication year - 1984
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1984.tb02650.x
Subject(s) - triticale , antigenicity , radioallergosorbent test , immunoglobulin e , food science , agronomy , antibody , biology , chemistry , immunology
Summary Specific IgE antibodies were demonstrated in the sera of six bakers with respiratory symptoms of asthma or bronchitis by the radioallergosorbent (RAST) assay. The specificity of the antibodies was found to be directed not only against the common flours (rye, wheat) used in the bakeries but also against triticale, barley, oat. corn and rice in some of the bakers. By using the RAST inhibition tests, cross‐antigenicity was shown to exist between different cereal grains. The degree of cross‐reactivity closely paralleled their taxonomic relationship and appeared to be in the following order of decreasing closeness: wheat, triticale, rye. barley, oat. rice and corn. The allergenic activity in the rye and wheat extracts was found to be distributed among various fractions of different molecular weights.