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Cross‐reactivity between Acacia (wattle) and rye grass pollen allergens
Author(s) -
HOWLETT B. J.,
HILL D. J.,
KNOX R. B.
Publication year - 1982
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1982.tb02526.x
Subject(s) - radioallergosorbent test , lolium perenne , pollen , acacia , allergen , immunoglobulin e , botany , biology , immunology , allergy , antibody , poaceae
Summary Immunoglobulin E (IgE), directed against components of Acacia (wattle) pollen, has been detected by radioallergosorbent tests (RAST) in the sera of some children and adults who develop allergic symptoms in the presence of flowering Acacia trees in Australia. All these subjects also had high levels of IgE directed against Lolium perenne (rye grass) pollen. Inhibition by RAST showed that most of the IgE molecules which bound to Acacia pollen components also bound to L . perenne pollen extracts, and to Glycoprotein I, the major allergen of L. perenne pollen. In these assays, the allergens have been immobilized on polyvinyl chloride microtitre trays: the sensitivity of this approach is compared to that of commercial RAST kits.