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Serum and salivary immunoglobulin A and free secretory component in ulcerative colitis
Author(s) -
MORRIS T. J.,
MATTHEWS N.,
RHODES J.
Publication year - 1981
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1981.tb02175.x
Subject(s) - ulcerative colitis , medicine , secretory component , immunology , candida albicans , colitis , secretory iga , antibody , proctitis , immunoglobulin a , saliva , gastroenterology , immunoglobulin g , biology , disease , microbiology and biotechnology
Summary Patients with ulcerative colitis have been investigated for evidence of defects in secretory immunity. Total serum IgA concentration, serum IgA antibody titres to Candida albicans , salivary IgA and free secretory component concentrations have been measured in thirty‐six patients with ulcerative colitis and thirty‐six normal controls. None of the parameters was significantly different between patients with proctitis and patients with extensive colitis or between the colitis patients and normal controls.