Premium
In vitro stimulation of lymphocytes in patients with chronic urticaria induced by additives and food
Author(s) -
VALVERDE E.,
VICH J. M.,
GARCÍACALDERÓN J. V.,
GARCÍACALDERÓN P. A.
Publication year - 1980
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1980.tb02153.x
Subject(s) - tartrazine , angioedema , stimulation , food additive , aspirin , chronic urticaria , medicine , in vitro , immunology , gastroenterology , chemistry , pharmacology , food science , biochemistry , pathology
Summary We studied the stimulation of lymphocytes in 258 patients with urticaria and/or angioedema using a series of food extracts and additives. Of this group, 238 revealed a positive response index (RI). There was a positive RI to additives in 18.4% of the cases, to food extracts in 35.2% and to both extracts and additives in 46.6% of the cases. A positive RI to both aspirin and tartrazine was revealed in 25% and to all the additives tested in 11% of the cases. Diets from which food extracts and additives were excluded achieved total remission in 159 (61.1%), partial remission in fifty‐seven cases (22%) and no remission in forty‐two (16.2).