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P 1 incompatibility in pigeon breeders
Author(s) -
RADERMECKER M.,
BRUWIER M.,
BURY J.,
FILLET G.
Publication year - 1980
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1980.tb02112.x
Subject(s) - antibody , biology , immunology , immunization , in vivo , genetics
Summary Pigeon breeders of the P 2 blood phenotype may develop anti‐P 1 haemagglutinins as a consequence of natural immunization to pigeon dust. The half‐life of labelled P 1 erythrocytes was determined in two P 2 pigeon breeders otherwise compatible except for the presence of anti‐P 1 antibodies and in four compatible controls without anti‐P 1 . The half‐life of tagged cells was within the normal range in one breeder but significantly reduced in the other, indicating that P 1 incompatibility may occur in vivo. Since anti‐P 1 antibodies are found in about 20% of P 2 pigeon breeders, it is suggested that this group may be prone to developing an incompatibility to transfused P 1 red cells.