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Angioedema responding to antiprotease treatment but without abnormalities of the complement system
Author(s) -
FREED D. L. J.,
BUISSERET P. D.,
LLOYD MARY J.,
PUMPHREY R. S. H.,
GARRETTS M.
Publication year - 1980
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1980.tb02075.x
Subject(s) - angioedema , complement (music) , medicine , complement system , immunology , complement component 5 , hereditary angioedema , intensive care medicine , biology , immune system , biochemistry , complementation , gene , phenotype
Summary Four patients suffered from chronic or recurrent angioedema, of sudden onset in adult life, associated with visceral pain and impossible to control by dietary means. In spite of normal complement function they respond very well to tranexamic acid therapy. Antiprotease drugs need not be restricted to cases of Cl s INH deficiency.