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Non‐specific reactions caused by diluents containing glycerol in nasal and bronchial challenge tests
Author(s) -
HAAHTELA T.,
LAHDENSUO A.
Publication year - 1979
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1979.tb01546.x
Subject(s) - glycerol , asthma , diluent , allergen , medicine , allergy , immunology , chemistry , organic chemistry
Summary Sixty‐one patients hospitalized because of asthma and/or allergic rhinitis were given nasal and bronchial challenge tests with diluents containing gylcerol. 62% of the patients with rhinitis and 37% of those with asthma gave positive reactions. Glycerol should therefore not be used in allergen extracts which are meant for challenge tests. The non‐specific effect of glycerol seems to be cumulative with increasing dose.