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Lymphocyte transformation in extrinsic bronchial asthma
Author(s) -
THOMSON N. C.,
MACDONALD CATHERINE,
KIRKWOOD EVE
Publication year - 1978
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1978.tb01501.x
Subject(s) - asthma , immunology , medicine , transformation (genetics) , lymphocyte activation , lymphocyte , biology , immune system , t cell , genetics , gene
Summary Lymphocytes from sixteen patients with extrinsic bronchial asthma and sixteen normal were investigated for their in vitro reactivity to stimulation with phytohaemagglutinin (PHA) and concanavalin A (Con A). No significant differences in maximum lymphocyte responses to PHA or Con A, either in the presence of foetal calf serum or autologous plasma, were found. The significance of these results in relation to T suppressor cell control of IgE formation is discussed.