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A prospective study of respiratory infection in asthmatic patients treated with beclomethasone dipropionate and sodium cromoglycate
Author(s) -
AGNEW R. A. L.,
WALKER D. J.,
PHILLIPS L. A.
Publication year - 1977
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1977.tb01440.x
Subject(s) - medicine , sodium cromoglycate , asthma , anesthesia , respiratory tract , upper respiratory tract infection , respiratory system , incidence (geometry) , beclometasone dipropionate , respiratory tract infections , respiratory disease , lung , physics , optics
Summary A prospective study of forty adult asthmatic patients attending two chest clinics in the City of Liverpool was undertaken. All patients had reversible airways obstruction and were under treatment with either beclomethasone dipropionate or sodium cromoglycate. Satisfactory symptomatic control was achieved in both groups of patients on a subjective basis, but there was a statistically significant ( P <0.001) reduction in the number of admissions to hospital in the treatment year compared to the preceding 12 months in the beclomethasone aerosol group. No increased incidence of lower respiratory tract infections or non‐specific sore throats was found in either group studied. No cases of clinical oral Candida infection occurred in the beclomethasone aerosol treated patients. It is concluded that beclomethasone dipropionate in aerosol form is not only a safe and effective method for symptomatic control of adult bronchial asthma but is also economically worthwhile as a means of reducing hospital admissions in this vulnerable group of patients.