Premium
The effect of a new anti‐allergic drug ICI 74, 9I7, given by aerosol, on nasal stenosis induced by allergen
Author(s) -
VILSVIK JAN SVERRE,
JENSSEN ARNE OLAV
Publication year - 1976
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1976.tb01933.x
Subject(s) - allergen , medicine , nasal administration , placebo , drug , nasal cavity , allergy , anesthesia , dermatology , pharmacology , immunology , surgery , pathology , alternative medicine
Summary Nasal airways resistance was measured in ten patients with allergic rhinitis during intranasal application of an extract of grass pollen. Pretreatment with placebo did not inhibit the increase in nasal airways resistance, whereas ICI 74,917 administered from a pressurized aerosol gave almost complete protection. ICI 74,917 was well tolerated and no evidence was obtained of local hyposensitization during the period of the study.