Premium
Elevated serum IgG4 levels in cystic fibrosis patients
Author(s) -
SHAKIB F.,
STANWORTH D. R.,
SMALLEY C. A.,
BROWN G. A.
Publication year - 1976
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1976.tb01902.x
Subject(s) - cystic fibrosis , subclass , medicine , incidence (geometry) , fibrosis , immunology , pathology , gastroenterology , antibody , physics , optics
Summary The quantitative measurement of the IgG subclass composition of the sera from sixteen patients with cystic fibrosis has revealed grossly elevated levels of IgG4 in seven patients. The possible significance of this observation is discussed in relation to recent reports of a high incidence of immediate‐type hypersensitivity in such patients.