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Late onset asthma due to inhalation of Aspergillus niger
Author(s) -
JOHNSON THOMAS F.,
REISMAN ROBERT E.,
ARBESMAN CARL E.
Publication year - 1975
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1975.tb01879.x
Subject(s) - aspergillus niger , inhalation , sputum , aspergillus , precipitin , asthma , medicine , histamine , immunology , microbiology and biotechnology , pathology , biology , antigen , tuberculosis , anesthesia , food science
Summary Clinical observations and immunological evidence are presented to support a diagnosis of late onset asthma due to exposureto Aspergillus niger in a 70‐year‐old man. Asthma occurred on only three occasions, each time approximately 6 hr after exposure to an area containing Aspergillus niger . His sputum culture contained the same organism. Immunological correlates using the Aspergillus niger extract included positive immediate and late skin tests, histamine release from leukocytes, and serum precipitins.