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Treatment of nasal polyps with intranasal beclomethasone dipropionate aerosol
Author(s) -
MYGIND N.,
PEDERSEN C. BRAKE,
PRYTZ S.,
SØRENSEN H.
Publication year - 1975
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1975.tb01848.x
Subject(s) - nasal administration , beclometasone dipropionate , medicine , placebo , nasal spray , nasal polyps , corticosteroid , anesthesia , nose , dermatology , surgery , pharmacology , respiratory disease , pathology , alternative medicine , lung
Summary In a double‐blind trial thirty‐five patients with moderately‐severe nasal polyposis were treated with intranasal beclomethasone dipropionate aerosol for 3 weeks. The dose given (400 γg/day) had only local effect on the symptoms. Judged by diary card scores the nasal symptoms were reduced to 52% of the pre‐trial level for the whole group. Corrected for the placebo effect the percentage was 68. The reduction of symptoms was equally apportioned to the three symptoms, sneezing, nasal secretion and blockage. The treatment was tolerated well, and it is concluded that intranasal treatment with beclomethasone dipropionate aerosol offers most patients with nasal polyps a good response without any risk of systemic steroid side‐effects.