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Half‐life of CINH in hereditary angioneurotic oedema (HAE) *
Author(s) -
BRACKERTZ D.,
ISLER E.,
KUEPPERS F.
Publication year - 1975
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1975.tb01839.x
Subject(s) - hereditary angioedema , medicine , gastroenterology , immunology
Summary The half‐life of 125 I labelled CINH was determined in patients with HAE and normal controls. There was no significant difference between these two groups. The half‐life in the HAE patients was 67.7 hr ± 4.9 hr (s.d.) and in the normals 64 hr± 1.4 hr (s.d.). This finding is consistent with a defect in synthesis as an explanation of the low serum C1NH levels in HAE patients.