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A fine structure study of some cellular components in allergic reactions
Author(s) -
TROTTER C. M.,
ORR T. S. C.
Publication year - 1974
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1974.tb01403.x
Subject(s) - degranulation , urticaria pigmentosa , mast cell , pathology , allergy , immunology , mast (botany) , medicine , chemistry , receptor
Summary Skin samples from patients with Urticaria pigmentosa, Urticaria both spontaneous and induced, and from normal individuals has been examined and mast cell ullrastructure described. The features of mast cells in skin are compared with those in nasal and bronchiolar tissue and distinguishing features areas follows. (1) Skin mast cells tend to have longer villous extensions of plasma membrane. (2) Granules in skin mast cells have very frequent crystalline inclusions; these are uncommon in other tissues examined so far. Degranulation of the mast cells was observed and appears similar to that seen in other tissues.