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Eosinophilic granuloma of the lung with sawdust and horse‐protein hypersensitivity
Author(s) -
GIRARD J. P.,
BOUZAKOURA C.
Publication year - 1974
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1974.tb01364.x
Subject(s) - horse , eosinophilic granuloma , granuloma , medicine , pathology , lung , inhalation , immunology , eosinophilic , allergy , granuloma formation , asthma , biopsy , pulmonary eosinophilia , lung biopsy , eosinophil , biology , paleontology , anatomy
Summary A typical case of pulmonary eosinophilic granuloma, ascertained by lung biopsy, is reported. Immunological studies showed multiple hypersensitivity against wood dust extracts, horse serum, horse hair and danders proteins. Inhalation of these two groups of substances reproduced most of the acute symptoms of the disease. Therefore, a causal relationship seemed highly probable. To our knowledge, this is the first case of pulmonary eosinophilic granuloma in which an allergic origin could be substantiated.