Premium
A clinical trial of beclomethasone dipropionate aerosol in children and adolescents with asthma
Author(s) -
SMITH JOHN MORRISON
Publication year - 1973
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1973.tb01330.x
Subject(s) - medicine , asthma , corticosteroid , beclometasone dipropionate , anesthesia , clinical trial , pediatrics , respiratory disease , lung
Summary A double‐blind cross‐over trial lasting 4 weeks of beclomethasone dipopionate aerosol in thirty‐nine children and young people with asthma already on oral corticosteroid treatment showed a significant beneficial effect which in most cases was maintained on continued open treatment for a further 4 weeks. An overall assessment based on several clinical observations and measurements suggested that twenty‐four (62%) were improved while having beclomethasone dipropionate. After a month on known beclomethasone dipropionate fifteen patients had stopped oral corticosteroid treatment and five had reduced the dose without relapse. Response to treatment was not related to total IgE levels. No serious side effects were noted.