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Effect of disodium cromoglycate on asthmatic reactions to alcoholic beverages
Author(s) -
BRESLIN A. B. X.,
HENDRICK D. J.,
PEPYS J.
Publication year - 1973
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1973.tb01311.x
Subject(s) - ingestion , disodium cromoglycate , asthma , medicine , inhalation , alcohol , sodium cromoglycate , oral administration , anesthesia , chemistry , biochemistry
Summary Eleven asthmatic patients with a history of asthma with or without rhinitis following the ingestion of alcoholic drinks were challenged by oral ingestion of the suspected drink, and some with equivalent amounts of ethyl alcohol. Asthma was provoked in six cases, four having falls in the FEV 1 of more than 15%. Three of the latter studied in detail gave immediate asthmatic reactions to the alcoholic beverage, but not to the ethyl alcohol tested by oral ingestion, and in one case by administration through a naso‐gastric tube. Pre‐treatment by inhalation of disodium cromoglycate inhibited the asthmatic reactions to the alcoholic beverages.