Open AccessStem cells and genetic disease
Author(s) -
MackaySim A.,
Silburn P.
Publication year - 2008
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.2008.00487.x
Subject(s) - stem cell , embryonic stem cell , biology , adult stem cell , induced pluripotent stem cell , kosr , transplantation , microbiology and biotechnology , stem cell transplantation for articular cartilage repair , immunology , medicine , genetics , gene
. Stem cell research is now a very broad field encompassing cells derived from all stages of life from the embryonic stem cells of the early blastocyst through to the adult stem cells of many tissues of the body. Adult stem cells from a variety of tissues are proving to be pluripotent and can differentiate into cell types different from the tissues from which they derive. Pre‐clinical animal models indicate that adult stem cells do not cause tumours, not even, teratomas when transplanted. These properties, combined with the possibility of autologous transplantation, indicate significant advantages over embryonic stem cells in many proposed clinical applications.