Open AccessCircadian Rhythms Are Suppressed In Hyperproliferative Mouse Epidermis
Author(s) -
Brown W. R.,
Furukawa R. D.,
Ramsay C. A.
Publication year - 1988
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1988.tb00854.x
Subject(s) - circadian rhythm , epidermis (zoology) , biology , rhythm , cell growth , period (music) , microbiology and biotechnology , medicine , endocrinology , anatomy , genetics , physics , acoustics
We examined the chronically hyperproliferative epidermis of the asebia (ab/ab) mouse for circadian rhythms in cell proliferation and in the rate of DNA synthesis, which is related to S phase duration. the curve for the circadian rhythm in cell proliferation for asebia epidermis was suppressed and distorted in comparison to that for BALB/cJ epidermis and in comparison to a composite curve produced by averaging the results from ten other published studies.