Open AccessProportions of Mitotic and Apoptotic Cells In A Range of Untreated Experimental Tumours
Author(s) -
Sarraf C. E.,
Bowen I. D.
Publication year - 1988
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1988.tb00770.x
Subject(s) - mitosis , apoptosis , biology , range (aeronautics) , mitotic index , microbiology and biotechnology , electron microscope , cancer research , biochemistry , optics , materials science , physics , composite material
. The quantitative aspect of apoptosis in experimental tumours is often neglected. In this study, the apoptotic and mitotic indices for a range of tumours have been determined at light microscope level. It has been found that the apoptotic levels fall into a consistent range for all tumour types and agree well with those described by previous workers. It is suggested that these might be basic parameters of tumour expansion, as relevant to growth kinetics as mitotic levels.