Open AccessPrediction of X‐ray induced mitotic delay and recovery of G 2 cells
Author(s) -
Easton D. M.,
Schneiderman M. H.
Publication year - 1987
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1987.tb01322.x
Subject(s) - mitosis , gompertz function , function (biology) , asynchronous communication , exponential growth , exponential function , kinetics , microbiology and biotechnology , biology , biological system , biophysics , physics , mathematics , computer science , mathematical analysis , statistics , classical mechanics , computer network
. A mathematical model is presented that predicts the delay of mitosis caused by X‐irradiation of an asynchronous, exponentially growing cell culture (data of Schneiderman & Schneiderman, 1984). In the model, based on Gompertz kinetics, the driving function to generate the curves is a simple exponential decay expression. For the delayed mitotic progress curves, this function characterizes the distribution of the time required for cells to enter mitosis.