Open AccessSleep Deprivation Alters the Cell Population Kinetics In the Jejunum of the Male Syrian Hamster ( Mesocricetus auratus )
Author(s) -
Jazwinska Elizabeth C.
Publication year - 1986
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1986.tb00685.x
Subject(s) - mesocricetus , hamster , jejunum , population , sleep (system call) , biology , kinetics , endocrinology , medicine , computer science , environmental health , operating system , physics , quantum mechanics
The proliferative and functional units of the jejunum were studied every 3 hr during 24 hr in groups of control and sleep‐deprived hamsters. Peaks in kinetic parameters were evident during the sleep period in control hamsters; in the absence of sleep, peak values were significantly reduced. Sleep deprivation was associated with reduction of G 2 to M flux and reduction of the circadian rhythm in mitotic index from 74% to 25%. the reduction in the number of cells passing through M was reflected by a drop in labelling index 9 hr later. These findings are consistent with the theory that sleep promotes restorative processes.