Open AccessContinuous maturation of proliferating erythroid precursors
Author(s) -
Mackey M. C.,
Dörmer P.
Publication year - 1982
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1982.tb01055.x
Subject(s) - mitosis , dna synthesis , cell cycle , compartment (ship) , microbiology and biotechnology , biology , cell growth , cell , restriction point , cell division , guinea pig , dna , cell cycle progression , immunology , genetics , oceanography , geology
. This study examines published steady state cell kinetic (mitotic and DNA synthesis phase) data from the recognizable proliferating erythroid precursors in humans, rats, and guinea‐pigs, and human neutrophilic precursors, for consistency with a continuous maturation‐proliferation model of the cell cycle. We find that these data are completely consistent with the hypothesis that maturation between morphological compartments may take place at any point in the cell cycle. A number of compartmental parameters are derived under this assumption.