Open AccessSELF‐MAINTENANCE ABILITY AND KINETICS OF HAEMOPOIETIC STROMA PRECURSORS
Author(s) -
Chertkov J. L.,
Gurevitch Olga A.
Publication year - 1980
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1980.tb00493.x
Subject(s) - stroma , kinetics , microbiology and biotechnology , biology , chemistry , immunology , physics , quantum mechanics , immunohistochemistry
The use of repeated femoral curettages and repeated passages of ectopic haemopoietic foci has demonstrated the capacity of stromal precursor cells for repeated formation of haemopoietic microenvironment. During this process the stromal precursors undergo no less than ten to twelve mitoses. Precursors of bone marrow stroma proliferating slowly, if at all, in normal mice are triggered into cell cycle, as revealed by suicide methods, during formation of the ectopic haemopoietic focus.