Open AccessEVALUATION OF FLOW CYTOMETRIC DATA OF HUMAN TUMOURS
Author(s) -
Beck H.P.
Publication year - 1980
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1980.tb00460.x
Subject(s) - flow cytometry , flow (mathematics) , dna , biology , immunology , mechanics , physics , genetics
Background signals and aggregation of cells affect flow cytometric DNA measurements to a great and mostly uncontrolled extent. These artefacts appear mainly in investigations of solid tumours leading to significant distortions in the results. Procedures are described that make possible quantitative corrections both of the background and of the cell aggregations