Open AccessPREDICTION OF THE COMPLETE GROWTH PATTERN OF HUMAN MULTIPLE MYELOMA FROM RESTRICTED INITIAL MEASUREMENTS
Author(s) -
Brunton G. F.,
Wheldon T. E.
Publication year - 1977
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1977.tb00316.x
Subject(s) - multiple myeloma , identification (biology) , drug administration , computer science , computational biology , biology , medicine , immunology , ecology
A method is presented for predicting the complete growth pattern of human IgG multiple myeloma from a few initial measurements of tumour cell number. This permits identification of patterns of undisturbed neoplastic growth in individual patients whose therapy cannot ethically be withheld for long periods. Since the unperturbed growth pattern is a necessary part of the information required for the prediction of individual patient response to alternative treatment schedules, the prospects for improved treatment of human multiple myeloma by optimal scheduling of drug administration are greatly increased.