Open AccessCELL KINETICS OF A CHONDROSARCOMA
Author(s) -
Dawson Anne,
Kember N. F.
Publication year - 1976
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1976.tb01304.x
Subject(s) - chondrosarcoma , kinetics , cell , mitosis , cartilage , cell cycle , cell growth , chemistry , biology , pathology , cancer research , microbiology and biotechnology , medicine , anatomy , biochemistry , physics , quantum mechanics
The cell kinetics of the transplantable DC‐II mouse chondrosarcoma have been studied by the pulse labelled mitoses method. The analysis gave the following estimates for the phases of the cell cycle: G, 10‐5 hr; S, 9‐5 hr; G 2 , 4 hr with an intermitotic time of 23‐5 hr. Consideration of the overall growth of the tumour indicated that the growth fraction and cell loss factor both had values of about 0–5. The results are compared with cell kinetic data from sarcomas and other cartilage tissues.