Open AccessOSCILLATION OF BLOOD MONOCYTE COUNTS IN HEALTHY INDIVIDUALS
Author(s) -
Meuret Gerhard,
Bremer Christel,
Bammert Joachim,
Ewen Jörg
Publication year - 1974
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1974.tb00902.x
Subject(s) - monocyte , oscillation (cell signaling) , compartment (ship) , immunology , biology , medicine , physiology , biochemistry , oceanography , geology
Daily examinations of monocyte blood counts in healthy individuals indicated the presence of a monocyte cycle. The cycle length was between 3 and 6 days. The predominant period was 5 days. A similar oscillation frequency resulted from a computer simulation of a feedback loop which linked the blood monocyte compartment (controlled variable) to the stem cell differentiation rate (controlling variable).