Open AccessA QUANTITATIVE STUDY OF THE MITOTIC ACTIVITY IN THE SUBEPENDYMAL PLATE OF ADULT RATS
Author(s) -
Hopewell J. W.
Publication year - 1971
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1971.tb01538.x
Subject(s) - subependymal zone , mitosis , biology , mitotic index , microbiology and biotechnology , andrology , physiology , medicine , anatomy
A quantitative study of the mitotic activity of the cells of the subependymal layer in the rat brain has shown that mitotic activity decreases with the increase in age of the animals. Mitotic activity is still found in rats 16 months old and in the case of animals of two strains of rats, of this age, the mitotic count is significantly higher in males than in females. The relationship between a reduced rate of brain growth and the decline in mitotic activity and the significance and importance of the higher mitotic count in the subependymal plate of 16‐month‐old males compared with similar females is discussed.