Open AccessKINETICS OF THE INNER ENAMEL EPITHELIUM IN THE ADULT RAT INCISOR
Author(s) -
Zajicek Gershom,
BarLev Moshe
Publication year - 1971
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1971.tb01525.x
Subject(s) - compartment (ship) , thymidine , epithelium , population , mitosis , enamel paint , chemistry , doubling time , biology , anatomy , andrology , cell , microbiology and biotechnology , dentistry , biochemistry , dna , medicine , genetics , oceanography , environmental health , geology
Rats were injected with tritiated thymidine and sacrificed at various time intervals up to 24 hr. the extracted incisors were decalcified, cut sagittally, dipped into liquid emulsion exposed for 14 days, developed and stained. the counting consisted of an exact mapping and numbering of the cells. The inner enamel epithelium consists of two compartments: proliferative and mature cells. the first may be further subdivided into blasts and metablasts. Each dividing blast yields one blast and one metablast. the metablasts continue to divide further, at least once, yielding again two metablasts. The kinetic parameters of this population are: generation time 22 hr, synthesis time 4.5 hr, mitotic time 30 min, G 2 time 2 hr and G 1 time 15 hr. the daily cell production of the proliferative compartment equals its size.