Open AccessCARTILAGE CELL PROLIFERATION IN THE TAIL‐VERTEBRAE of NEW‐BORN RATS
Author(s) -
Dixon B.
Publication year - 1971
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1971.tb01514.x
Subject(s) - epiphysis , cartilage , cell growth , cell cycle , anatomy , cell , chemistry , microbiology and biotechnology , biology , biochemistry
Cartilage cell proliferation has been studied in the tail‐vertebrae of new‐born rats. At 1 day the median cycle time for cartilage cells was about 22 hr; G 1 + 1/2M, S, and G 2 + 1/2M being 6.8 ± 2.5, 11.6 ± 2.2, and 4.6 ± 2.0 hr respectively. At 7‐10 days, cell proliferation is confined mainly to the lower half of the epiphysis. Here cycle times are longer, about 3 1/2 days in the most active region. Differences in cycle times appear to be due to either a lengthening of G 1 or the entry of cells into a resting state. Changes in cartilage cell kinetics are discussed in relation to the structure and function of the epiphysis.