Open AccessAUTORADIOGRAPHIC STUDIES OF EOSINOPHIL KINETICS: EFFECTS OF CORTISOL *
Author(s) -
Andersen Vagn,
BroRasmussen Frede,
Hougaard Kjeld
Publication year - 1969
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1969.tb01000.x
Subject(s) - eosinophil , labelling , endocrinology , medicine , steroid , corticosterone , steroid hormone , hydrocortisone , corticosteroid , chemistry , immunology , biology , hormone , biochemistry , asthma
The effect of cortisol administration upon the labelling of blood eosinophils was studied in rats given a single injection of 3 H‐thymidine. One dose of cortisol did not change the subsequent course of labelling of eosinophils, whereas steroid treatment for 3 days resulted in a delay of the most heavily labelled class. The results seem to indicate that cortisol causes a reversible sequestration of blood eosinophils; and that long‐term steroid administration may delay the release of eosinophils from the bone marrow into the blood.