Open AccessCELL POPULATION KINETICS OF THE RECOGNIZABLE ERYTHROID CELLS IN THE RAT
Author(s) -
Tarbutt R. G.,
Blackett N. M.
Publication year - 1968
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1968.tb00194.x
Subject(s) - thymidine , population , kinetics , cell , transit time , chemistry , biology , microbiology and biotechnology , biophysics , biochemistry , physics , dna , medicine , environmental health , quantum mechanics , transport engineering , engineering
The cell population kinetic parameters defining a simple model of the recognizable part of the erythroid system have been determined. Experimental results using tritiated thymidine and radioactive iron autoradiography have provided estimates of the number of cell divisions, transit times and flow rates for all the recognizable stages of the erythroid system. The accuracy of the estimates and the validity of the model employed are discussed.