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Revaccination of children after completion of standard chemotherapy for acute lymphoblastic leukaemia: a pilot study comparing different schedules
Author(s) -
Lehrnbecher Thomas,
Schubert Ralf,
Allwinn Regina,
Dogan Kader,
Koehl Ulrike,
Grüttner HansPeter
Publication year - 2011
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.2010.08522.x
Subject(s) - medicine , chemotherapy , tetanus , diphtheria , pediatrics , poliomyelitis , acute lymphocytic leukemia , induction chemotherapy , vaccination , lymphoblastic leukemia , immunology , leukemia
Summary Given that a significant proportion of children with acute lymphoblastic leukaemia (ALL) lose immune protection to tetanus, diphtheria, and poliomyelitis, revaccination is indicated after chemotherapy. Our randomized pilot study comparing different revaccination schedules suggests that children with ALL might be revaccinated with non‐live vaccines as early as 3 months after chemotherapy.