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Outcome of children with sickle cell disease admitted to intensive care – a single institution experience
Author(s) -
Bartram Jack L.,
Thein Swee L.,
Gardner Kate,
Egberongbe Yaya,
D’Silva Pam,
Height Susan E.,
Dick Moira C.,
O’Driscoll Sandra,
Rees David C.
Publication year - 2010
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.2010.08272.x
Subject(s) - medicine , pediatrics , acute chest syndrome , disease , intensive care , exchange transfusion , cardiorespiratory fitness , blood transfusion , sickle cell anemia , emergency medicine , intensive care medicine
Summary We retrospectively audited children with sickle cell disease (SCD) admitted to paediatric intensive care (PICU) at King’s College Hospital between January 2000 and December 2008. Forty‐six children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7·6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.