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The use of intravenous iron in patients with cancer‐related anaemia
Author(s) -
Littlewood T. J.,
Alikhan R.
Publication year - 2008
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.2008.07118.x
Subject(s) - intravenous iron , medicine , iron deficiency , placebo , anemia , erythropoiesis , intensive care medicine , cancer , hematinic , alternative medicine , pathology
Summary Intravenous iron has become the standard of care in patients with renal failure receiving treatment with erythropoiesis stimulating agents (ESAs) to treat true and functional iron deficiency and to prevent its development in haemodialysis patients. In cancer‐related anaemia, several recently published, randomised studies suggested that intravenous iron improved haemoglobin response rates in ESA‐treated patients compared to those treated with oral iron or placebo. The data supporting the efficacy of intravenous iron instead of oral iron in this setting are increasingly persuasive but larger randomised trials are needed before definitive recommendations are made.